aida software version 4.50.010 (Raytest GmbH)
90
Structured Review
Raytest GmbH
aida software version 4.50.010
Aida Software Version 4.50.010, supplied by Raytest GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aida+software+version+4%2E50%2E010/aida+software+version+4+50+010/pm33483427-87-27-31
Average 90 stars, based on 1 article reviews
Aida Software Version 4.50.010, supplied by Raytest GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aida+software+version+4%2E50%2E010/aida+software+version+4+50+010/pm33483427-87-27-31
Average 90 stars, based on 1 article reviews
aida software version 4.50.010 - by Bioz Stars,
2026-10
90/100 stars
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Imaging:Article Title: Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles. Article Snippet: Activation of pregnane X receptor (PXR) results in the induction of first-pass metabolism and drug efflux.. Hereby, PXR may cause adverse drug reactions or therapeutic failure of drugs.. PXR inhibition is thus an attractive option to minimise adverse effects or to improve therapeutic efficiencies; however, only a limited number of antagonists have been identified so far. Article Title: Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor. Article Snippet: of PXR target gene expression was analyzed in primary human hepatocytes.. Ligand binding to PXR was investigated by molecular docking and limited proteolytic digestion.. We show here that CINPA1 induced the assembly of the PXR ligand-binding domain, released co-repressors from and recruited co-activators to the receptor. Article Title: Nelfinavir and Its Active Metabolite M8 Are Partial Agonists and Competitive Antagonists of the Human Pregnane X Receptor. Article Snippet: Input PXR-LBD protein and protected proteolytic fragments were detected by scanning the imaging plates with the Software:Article Title: Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles. Article Snippet: Activation of pregnane X receptor (PXR) results in the induction of first-pass metabolism and drug efflux.. Hereby, PXR may cause adverse drug reactions or therapeutic failure of drugs.. PXR inhibition is thus an attractive option to minimise adverse effects or to improve therapeutic efficiencies; however, only a limited number of antagonists have been identified so far. Article Title: Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor. Article Snippet: of PXR target gene expression was analyzed in primary human hepatocytes.. Ligand binding to PXR was investigated by molecular docking and limited proteolytic digestion.. We show here that CINPA1 induced the assembly of the PXR ligand-binding domain, released co-repressors from and recruited co-activators to the receptor. Article Title: Nelfinavir and Its Active Metabolite M8 Are Partial Agonists and Competitive Antagonists of the Human Pregnane X Receptor. Article Snippet: Input PXR-LBD protein and protected proteolytic fragments were detected by scanning the imaging plates with the |